DPCstruct | MC12426

Metacluster Properties and Pfam Annotations

Number of structural domains100
Mean domain length (aa)136 ± 22 aa
Standard deviation of domain lengths22.15
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.92
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.52
Pfam Score93.00
Assigned Pfam label(s) CL0431- CL0448

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0V0SNP4 503-618 KRVQAAHYKQDEVQVHCYDEYKAHVDRTGLVSGQKARVRIFCLAFVSGMPWVEIGLNDRRREGLEVVRRKDIMPMHTDRWIRLEQCE…
A0A0R3PIY7 93-220 STIEDILFKCPAKRETKPVYKQDEVQIHCYDEYSAFIDKEGILSQQKARVRLFCLAFVTGSPILEIGLNDRRRQGKEIVRRKDILPM…
A0A2P6NJ18 117-288 None
A0A1V9ZPX2 911-1039 None
A0A044U4B9 1226-1340 None
A0A813FGT3 346-483 None
A0A2H5P4M2 1-173 None
A0A5E4ABN6 100-228 None
A0A3Q7EP44 133-278 None
A0A482UWN7 19-156 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.