DPCstruct | MC12425

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)450 ± 31 aa
Standard deviation of domain lengths30.94
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score77.60
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)43.47
Pfam Score100.00
Assigned Pfam label(s) PF12473

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4X7C6 274-727 NFWGCSQTQVCPPIITQERSTQWTTVSGDRVIVQFDHCRDFVIPICEEFIEHCAEGALSVEVWGHRSAGFTSSIPTTLDVVDSQLAK…
A0A0R3PGF7 1-511 MLVVAPVFNPPQTSESQIQQTTFVFDHEKDFKVIVTEEFLEYVQDDALSIEVWGHRNGGVLEMGEPRLDAEEKNKSLQARWSEVSRR…
A0A834PU01 570-1028 None
F1KQE1 152-636 None
A0A0M3IPH9 40-511 None
S4RE50 289-741 None
A0A4W5Q777 19-431 None
A0A6H5HKJ0 456-864 None
A0A7R9PK53 687-1095 None
A0A815B7T5 332-765 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.