DPCstruct | MC12421

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)139 ± 9 aa
Standard deviation of domain lengths9.43
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score68.67
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)33.49
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q19281 19-162 KSGNPYKTKKYKCVEVSDDEEIRIVPKKKPVTSKYPWKTEEEKINRKNEDFRSTESIEMPMAKKVKTQKISTTTPPTVSDVQRDSKG…
A0A0R3PDV8 1-143 MRLLVILVACSSTGYAYENKNPLKTKKYKCLEVDDEMEIQIVPKQVIKGKAMTVFQRPLRKENRGRPIVSQKAQDIPRDKEGRQLLL…
A0A0N5ALY9 38-157 None
A0A0K0EBJ4 64-215 None
A0A1I7RKQ3 75-211 None
A0A3P7JG73 1-128 None
A0A7E4ZTX3 139-280 None
A0A0K0ESA2 281-422 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.