DPCstruct | MC12416

Metacluster Properties and Pfam Annotations

Number of structural domains115
Mean domain length (aa)171 ± 29 aa
Standard deviation of domain lengths28.97
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.67
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)31.90
Pfam Score84.44
Assigned Pfam label(s) CL0599- CL0158

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A452XFA8 10-166 IMWTMGDDFNYQYAESWFRNMDRLIHYVNKDGRVHALYSTPSIYTDAKHASNESWPLKQDDYFPYADSTNAYWTGYFTSRPTFKGYV…
A0A6P7HDP6 12-169 ITMGEDFNYQDAATWFKNLDKLISYANLRQSNGSRYNLIYSTPSCYVKAIYDETKGKKKWYVKQDDFFPYASDPHAFWTGYFTSRPT…
A0A815T6D4 1-162 None
A0A821ES73 115-312 None
A0A6P8CAY3 184-373 None
A0A1B0C107 27-263 None
A0A654HKJ7 61-241 None
A0A7R9Q162 62-232 None
A0A7R9PXK6 162-381 None
A0A7R9KAU0 223-354 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.