DPCstruct | MC12406

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)185 ± 28 aa
Standard deviation of domain lengths28.14
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score77.67
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)29.20
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D0RM47 261-473 PPCQGICDVFSCEHGSCNHPCSDPCAACTERCSWSCKHSGECSLPCGAPCNRRLCDLRCTKALTCGHQCPSVCGEDCPSREFCHICG…
A0A6P7H5I1 1-159 CKEACVRKCEHQECKRRCGEICNVPPCYKPCPKKIRRCRHPCIGFCGDPCPSLCRICNAEELTEFFFGTEDEEDARFVLLVDCGHIL…
A0A6J3C2U0 2-131 None
A0A7M7N432 267-473 None
A0A2I1E534 502-698 None
A0A2G8LS10 58-249 None
A0A835Y6R4 9-206 None
R7QII7 6-212 None
A0A0M3I8I2 367-570 None
A0A8A3NXW6 56-279 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.