DPCstruct | MC12400

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)221 ± 19 aa
Standard deviation of domain lengths19.26
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score81.86
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)40.90
Pfam Score100.00
Assigned Pfam label(s) PF12623

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q6DA79 2-198 MFLSISTQHQEASDLGYLFHKHPDRVHKLDLPFGKAIVFFSELSVERSTIVLQFEVDSIGLVRGFGGRDNSQVDLYVNDRPYVSSSL…
A0A2T4DU27 1-228 MLLNISTTHNPATDLSFLLHKHPEKLQSVELATGKAHIFYSEATTDNCSVNLLLDINPIELVKNNRNNSSDFALAHYVNDRPYVASS…
A0A1H2D1L1 2-263 None
A0A7S8EB50 4-198 None
A0A1Z4TG39 1-222 None
A0A1C6QC08 49-281 None
A0A841GWH0 1-199 None
A0A4R2JMZ3 1-225 None
A0A229TAV2 214-436 None
A0A7X0D3B3 1-230 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.