DPCstruct | MC124

Metacluster Properties and Pfam Annotations

Number of structural domains16132
Mean domain length (aa)192 ± 37 aa
Standard deviation of domain lengths37.03
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.65
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.64
Pfam Score94.49
Assigned Pfam label(s) PF04931- CL0219- PF11899- PF05890- CL0273

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4D8TUW6 2-185 LDLACGFGFFGREIYRRGAAGVVGVDISEKMIELAREESRKYGDPLEFHVRDVANMEPLGQFDLVNAAWLFNYADSVENLRKMFKVV…
A0A1G6WKE3 47-254 KWATGIYDLVIEYFTRGRALRRLSVDAIAPAAGEAILDLGCGTGELSLALAQTEPKSSITGYDIDPEILEIARNKMGLQGEVSAVTF…
A0A2J8AA05 53-324 None
A0A7U4QLZ7 229-452 None
A0A811N0I3 38-199 None
A0A7W1E5H6 6-171 None
A0A811MZD3 65-241 None
A0A811MFW6 114-301 None
A0A654HUP7 357-538 None
A0A811MFI2 18-243 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.