DPCstruct | MC12390

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)159 ± 35 aa
Standard deviation of domain lengths34.92
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score90.47
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)26.53
Pfam Score100.00
Assigned Pfam label(s) PF06253

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A497AUT4 136-315 SLMIAAHAQLARHYGLPSRSGGALTDASYPDAQAGFESMLALLTTINSGVDFVLHAGGILSSYLAFSYEKFVLDDEMCGMVRRLQRG…
A0A509L3J3 55-235 ASPEDAKHTAIVTALSQYYNIPCRSQGALTESFSLDYQAGMESSMMLTTAALSGVHVSLHACGTYGSMLAMSFEKFIADEDLCCAIK…
A0A3G1L296 3-127 None
A0A0E2NWW1 3-264 None
A0A538IUJ3 413-600 None
G1V4N2 10-155 None
X1J9B1 1-96 None
A0A2E8H681 175-355 None
A0A356V653 60-203 None
A0A350WSY4 31-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.