DPCstruct | MC12386

Metacluster Properties and Pfam Annotations

Number of structural domains407
Mean domain length (aa)247 ± 50 aa
Standard deviation of domain lengths50.47
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score85.99
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.64
Pfam Score99.02
Assigned Pfam label(s) PF06155- CL0111- CL0029- PF05141- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A433QB13 1-197 None
A0A0J9WJI9 39-296 None
K0THE2 661-795 None
A0A820V6U5 2-135 None
A0A1Z5SZ10 385-699 None
M1W7I9 7-242 None
A0A4Y7LZS8 408-598 None
A0A486XSI2 46-327 None
A0A812NID8 14-272 None
A0A226EQT7 22-239 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.