DPCstruct | MC12386

Metacluster Properties and Pfam Annotations

Number of structural domains407
Mean domain length (aa)247 ± 50 aa
Standard deviation of domain lengths50.47
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score85.99
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.64
Pfam Score99.02
Assigned Pfam label(s) PF06155- CL0111- CL0029- PF05141- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V1ADX8 97-371 None
A0A7Z1Q7B2 39-267 None
A0A812VHL0 22-325 None
A0A812U011 394-699 None
A0A2R4XL67 217-481 None
A0A5B0WNY0 281-537 None
A0A3B9R293 22-357 None
A0A2E4DWJ4 2-266 None
M7UCF8 286-521 None
A0A2U3EMC2 49-345 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.