DPCstruct | MC12384

Metacluster Properties and Pfam Annotations

Number of structural domains58
Mean domain length (aa)120 ± 20 aa
Standard deviation of domain lengths20.33
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score93.69
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.58
Pfam Score84.29
Assigned Pfam label(s) CL0063- CL0106

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A656H0T3 158-266 NPDQPKTVFGFLCAALARRRAQGTPAFTLMSCDNLPHNGAVTRKALLAFATLRDAELHDWIKANVSFPNAMVDRITPMTSAAHRLQL…
W4UI44 172-295 STAMGLVTALLVQRFHAGATPVAVVSCDNFSHNGDMLRTSVLTIVAEWEKRGVIDHRVVEWIAEKVEFPISVIDKITPAPSQKVAEQ…
W4U5X0 10-108 None
U6LW67 6-96 None
A0A4U9CV90 49-181 None
A0A0A3YKM0 11-141 None
A0A447PUB1 46-152 None
A0A815N1C4 259-404 None
A0A6L5X4B5 175-322 None
A0A377DB53 96-202 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.