DPCstruct | MC12381

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)69 ± 5 aa
Standard deviation of domain lengths4.73
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score93.84
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)51.41
Pfam Score100.00
Assigned Pfam label(s) PF00521

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D4M7I5 118-189 TMVRLAQDWSLRYCLVDGQGNFGSVDGDRAAAMRYTEARLHELGELMLADIDEDTVEWGPNFDESLKEPLSL
A0A1E4CKW4 88-158 LVRMAQPWVMRYPLIFGQGNFGSLDGDSPAAYRYTEAKLTAVAMEFVQELGQETVDMRRNFDDSQDEPVVL
W4VE73 3-70 None
A0A2V6E1I9 37-108 None
A0A1A9Z1G2 2-69 None
A0A0H1SC17 2-75 None
A0A0K2RDV5 116-175 None
A0A4V6KUM3 100-161 None
A0A6D0ELB3 3-65 None
A0A3N5MJD8 86-157 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.