DPCstruct | MC12379

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)95 ± 14 aa
Standard deviation of domain lengths13.50
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score91.79
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)34.92
Pfam Score100.00
Assigned Pfam label(s) CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W4UEQ4 1-95 MTTAVYIEVNHEDLATVGAFVREGVHRPVFDLAMIFAANINYDGCTAYLHLNERVMETLRAAETQIRPLQRRGTKVLLSLLGNHERR…
D4IQ34 345-429 IRNICYFEVNDCNPLNAIEYILEDGQPFFDAVVLFAGNINWDASKQKVYMNANPNVQALLDNSEELLQPLRKKGIKVLLDILGNH
A0A1H8YDL8 86-166 None
A0A3D9DQK7 27-112 None
A0A173W8V9 41-137 None
A0A7V8F415 1-113 None
A0A1Y3VF10 1-129 None
A0A4Q0ISU4 195-279 None
R6EC92 111-195 None
A0A6G7LSJ0 109-210 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.