DPCstruct | MC12374

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)81 ± 10 aa
Standard deviation of domain lengths10.18
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.78
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)31.97
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D5Z5H5 124-207 INGPAWAGDDLAGMLAGRVLPFVQDDAQQNVWANWNADWRDVFILDRAGQLANRINLTGFNPDPGVNQGQNYALLKSMFLDARG
A0A381ZML6 5-78 EGEISGMIQNRVLPWAQDNEDSHVWDTWNITLRDFIVLDINGDFFYKINLTDVDPSIESNYENLKQLLLDARSN
A0A2E5JQS2 4-65 None
A0A2E6VQB7 10-85 None
A0A2D5UQV0 19-105 None
A0A2E8D4Q8 1-101 None
A0A2D6LYX8 1-87 None
A0A849Z3P7 16-93 None
A0A2V5MWS4 11-88 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.