DPCstruct | MC12372

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)148 ± 29 aa
Standard deviation of domain lengths29.11
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.24
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)41.29
Pfam Score100.00
Assigned Pfam label(s) PF00228

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
P12940 2-121 GKKRPWKCCDEAVCTRSIPPICTCMDEVFECPKTCKSCGPMGDPSRRICQDQYVGDPGPICRPWECCDKAICTRSNPPTCRCVDEVK…
A0A3B6EBP3 48-191 AAASRPWDCCDNTICTRSLPPICICLDEVDECASTCMACVPSVSNPFRRVCGDRYYGDPGPKCTYNTVAGDNNDDALVAAAAEEEKP…
A0A077RU50 43-184 None
A0A453DSU2 2-110 None
F2DJ59 17-204 None
A0A0A9PJC7 23-237 None
A0A077RU58 4-127 None
F5BCP7 11-172 None
A0A0D3EJ36 115-243 None
A0A835BZM4 80-208 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.