DPCstruct | MC12371

Metacluster Properties and Pfam Annotations

Number of structural domains118
Mean domain length (aa)488 ± 108 aa
Standard deviation of domain lengths107.83
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score78.81
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)24.79
Pfam Score89.12
Assigned Pfam label(s) PF10146- CL0027- CL0031- CL0266- PF12578

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3R6Z9M4 30-487 None
A0A6H5G5T9 26-517 None
A0A814JCD7 36-497 None
A0A7J7Y169 2-497 None
A0A455B326 7-469 None
A0A183N6U5 28-294 None
A0A131ZUS1 116-860 None
A0A409XR43 38-570 None
A0A4E0RRH2 557-976 None
A0A7S3ZFE5 165-734 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.