DPCstruct | MC12371

Metacluster Properties and Pfam Annotations

Number of structural domains118
Mean domain length (aa)488 ± 108 aa
Standard deviation of domain lengths107.83
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score78.81
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)24.79
Pfam Score89.12
Assigned Pfam label(s) PF10146- CL0027- CL0031- CL0266- PF12578

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A444U4L4 72-588 None
W4G1N8 426-806 None
A0A814YS36 357-862 None
L8GQW9 109-577 None
A0A1I8JHC6 273-810 None
A0A1I8JJ01 10-579 None
T1IWR3 92-650 None
A0A1J1HER9 562-1131 None
A0A0P5PPZ0 41-599 None
A0A7M3REJ0 101-536 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.