DPCstruct | MC12371

Metacluster Properties and Pfam Annotations

Number of structural domains118
Mean domain length (aa)488 ± 108 aa
Standard deviation of domain lengths107.83
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score78.81
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)24.79
Pfam Score89.12
Assigned Pfam label(s) PF10146- CL0027- CL0031- CL0266- PF12578

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0W8DZ82 15-566 TVSASRSINAYTPTRLVVKFKDLRSWTLGGDVTRLLPALNRHAYVDTPLNLFAFTSIGAMQEDLQGHALYDLYEDFARMGVALRDGS…
A0A6J1UIA5 12-459 EQRLEIFQNLITRAFPLSHGLPFFAFTYKEKFPTNGWKVYDPVAEYKRQGLPNESWKISKINSMYEFCDTYPAVLVVPTSVKDEDLS…
A0A6P4EEV9 61-700 None
A0A099P6S6 195-576 None
M2RDT6 481-915 None
A0A6P8IBS5 227-783 None
A0A4W4DXH8 3-567 None
A0A7S2CF63 1-323 None
K3WV89 2-322 None
A0A7R9KGB5 134-560 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.