DPCstruct | MC12368

Metacluster Properties and Pfam Annotations

Number of structural domains521
Mean domain length (aa)162 ± 34 aa
Standard deviation of domain lengths34.24
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.93
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)22.58
Pfam Score99.69
Assigned Pfam label(s) CL0010- CL0229- PF10198

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4X2LIW6 107-234 None
D8M652 114-291 None
A0A1Y2BR22 89-260 None
A0A2G9V074 179-345 None
A0A4Q2ZSN0 271-399 None
A0A1B6CJQ5 936-1096 None
A0A3Q7YF60 443-630 None
A0A540KN38 1-263 None
A0A814WDU2 209-379 None
A0A7J5Y1U7 411-556 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.