DPCstruct | MC12368

Metacluster Properties and Pfam Annotations

Number of structural domains521
Mean domain length (aa)162 ± 34 aa
Standard deviation of domain lengths34.24
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.93
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)22.58
Pfam Score99.69
Assigned Pfam label(s) CL0010- CL0229- PF10198

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0W8DQX7 9-170 DQGFLDDPIVQCEKCSVAVHQYCYGIESVPEGDEPWFCDFCTEPNGPSADATCELCPLKRQKSAFKKTVEGKWVHVVCALWAPGVQF…
A0A084VH88 2-119 TKTCFLCKSSEDDELLYGKFYTKYRISVHYYCLLLSSNLVQNGVNDEVGIFGFLEADIRKENQRTKSCRCYICKQMHANIFCCAKKC…
A0A0V0QFA6 23-222 None
A0A1Z5RNB3 1-164 None
A0A0K0DRY5 26-251 None
A0A0K0EDE0 1739-1857 None
A0A0N1I986 326-470 None
A0A061QLU9 150-331 None
A0A3N4IFA8 518-668 None
A0A672UD53 9-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.