DPCstruct | MC12362

Metacluster Properties and Pfam Annotations

Number of structural domains124
Mean domain length (aa)160 ± 32 aa
Standard deviation of domain lengths32.09
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score78.26
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)27.45
Pfam Score99.44
Assigned Pfam label(s) CL0010- PF04065

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q2I961 521-696 QFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLARYG…
A0A0W8DD00 345-491 PQLTEEQKQVLRLIDESFHFIPESRDSEKANRYVPRNLYPTPASFPATPSTLFSSAPIFEKLDVDTLFFIFYYQQGSYQQYLAAREL…
A0A7J6Q3D4 415-563 None
A0A1R0H0Z7 402-569 None
A0A1B8EP07 728-890 None
A0A1I8IPL1 27-152 None
A0A7S3JKN1 1-106 None
A0A1I8F8E0 101-232 None
A0A1Q9CE26 332-484 None
A0A444WWW9 12-124 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.