DPCstruct | MC12357

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)141 ± 25 aa
Standard deviation of domain lengths24.63
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score88.15
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)25.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W2Z0S9 177-295 LSQIHDLLTRRWRDSQATLALRDFYPYWFRNREDPTAGKLLVLDPTDSAEGVHAMFFDDNILPHDAHIVDARYAHNDSALSFAETRE…
A0A0W8D420 25-159 TVQIVQGLSQIHDLLTRRWRDSQATLALRDFYPYWFRNREDPTAGKLLVLDPTDSAEGVHAMFFDDNILPHDAHIVDARYAHNDSAL…
B7G4B5 265-374 None
A0A5K4F8S7 327-517 None
A0A813FUT8 183-334 None
A0A7S0ABU2 148-302 None
A0A7S2JPQ4 27-144 None
A0A7S2S4A4 4-91 None
A0A812IZU0 259-435 None
A0A7R9ZQ55 353-494 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.