DPCstruct | MC12354

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)75 ± 6 aa
Standard deviation of domain lengths6.28
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score86.92
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)48.88
Pfam Score100.00
Assigned Pfam label(s) CL0061

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183DMX2 1-74 MELCSFHSCSKGYMGECGLRGGYVEVLNMHPDVFKHFKKMISAKLCPTVLGQIVMDCVANPPKPGDPSYNLWIK
A0A7R9BFS1 521-597 LELASFMSSSKGYMGECGLRGGYAEIVNFDDDVRAMFLKSISAKLCPTVLGQATMDVVVNPPRAGEPSFELYAAEKK
A0A3L6DJB8 35-127 None
A0A7S2H214 97-171 None
A0A821VTM2 1-64 None
A0A817RB17 438-514 None
A0A835HK54 38-112 None
A0A7R9KKU0 114-188 None
A0A2N9INC1 789-863 None
A0A166CAB1 3-77 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.