DPCstruct | MC12350

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)160 ± 6 aa
Standard deviation of domain lengths5.67
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score77.47
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)47.03
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183DI18 2-160 RQVQTQNNKSVNEALNQVLIDEEDYAGLRASIDAYDNFDNIALAQQLEKHELLEFRRISAYLYKGNNRWKQSVELCKKDKLYKDAME…
A0A7S0T5V6 96-248 PPEVVEALLDVYFAEEALLHLRELIDMMRDFDQLALSERLENHPNAEFRQLGVELHKRGGRHERALELAKKEKLWKDAIGVAAHSED…
A0A4W5P6Y9 266-423 None
A0A2S4UMU0 77-229 None
A0A0P0XY45 460-619 None
A0A3L6GAD8 325-488 None
Q10161 1450-1607 None
A0A1I8FH54 543-712 None
A0A446RZG1 153-325 None
A0A811QKC7 237-397 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.