DPCstruct | MC12343

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)88 ± 7 aa
Standard deviation of domain lengths7.31
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score85.84
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)52.20
Pfam Score83.33
Assigned Pfam label(s) CL0023- PF02889

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183JFZ7 289-377 TPQILNFTIPLYEPYPTQYFVRILSDCWLGTDSTCPISLKRLILPSSDPPHTDLLKLQPLPVTALKNANYELLYNFPYFNPIQTQLF…
A0A822GLS7 82-177 KQVVTKEQQFLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPVSALGHREYEMLYKFTHFNP…
A0A0P0VUP0 107-188 None
E4YRB2 142-221 None
A0A813KE17 2-91 None
A0A226MFP0 188-266 None
U6KM92 186-276 None
U6KAI7 407-497 None
A8JJC3 212-308 None
A0A820FEH8 1-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.