DPCstruct | MC12328

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)146 ± 20 aa
Standard deviation of domain lengths19.62
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score69.40
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)33.86
Pfam Score100.00
Assigned Pfam label(s) PF12024

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A182T0C9 28-165 PHTKFEAFVDDLTADEVLEQVQSAALNARTKLLKRKSAHKLGFLRQHKDGTTSMKILLDTKSEGGEGGPERTVTLGAHTGKLQYGTG…
A0A0B1RRR0 1-112 MTPDDCLRAADPAARPRLSTRLPNAKLAFLDNKDGATVLNVIGETEKKGIKLGDIVGPLEEGTPGMLSLGDHRLSGQSMITYLNYGP…
A0A177AVB9 141-256 None
T1KJ57 79-248 None
E9FUK4 115-268 None
A0A183HI99 1-153 None
A0A1A8MMA9 174-344 None
A0A1I7UJJ3 170-320 None
A0A2S2QMA4 103-250 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.