DPCstruct | MC12319

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)125 ± 7 aa
Standard deviation of domain lengths7.43
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score79.61
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)29.56
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R8Q8J7 1-125 MPGMVLFRRRWSVGSDDLVLPAFFLFVLHCIWLVVLSVVLFGLPYSSEQSCSVTLVDHGRGYLGILVSCLICESAIMWLSMRGSILY…
A0A183CWN0 1-118 MPSLVVFGRRWNIASDDFVFPSLSEALVRLAWVTTTCIIFMLKKWRSCADQQFLIFIFSLIGVNSVTVLVCFILALASARGSILEPQ…
A0A5N5T6V5 1-126 None
A0A182MP32 21-144 None
A0A2R2MQZ4 1-135 None
A0A1B6CRZ8 1-122 None
A0A0V1DF00 1-118 None
A0A6S7JR12 1-144 None
A0A504YG01 1-122 None
A0A087SHW4 1-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.