DPCstruct | MC12308

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)103 ± 17 aa
Standard deviation of domain lengths16.70
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score85.41
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)33.73
Pfam Score60.00
Assigned Pfam label(s) CL0022- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0A1TYK2 1-102 MKRVDVFSMQIVAKYFQFITDYLYIIQVCKKYKFLLDRFRINPIRISPKYKPLFTHIQTQIVFTPYDIIVPVDRHIFLYYVSYQEYK…
A0A0A1UC92 1-98 MSRLDVYHMMIVSQYFLCLNDFITLEMVKRKFKNNIEKFQFNPIPINKKTIKYFTHIETLNLWSKEDERFGNYIFDKKNFISHQKVN…
L7FNH4 1-125 None
L7FNZ8 2-91 None
M2SD96 3-88 None
B0E920 1-103 None
B0EQL6 1-103 None
B0ELN9 312-423 None
B0ERK2 1-131 None
M7VW34 13-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.