DPCstruct | MC123

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)123 ± 18 aa
Standard deviation of domain lengths17.70
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score84.21
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)25.99
Pfam Score100.00
Assigned Pfam label(s) PF02810

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A517XWR9 25-138 HKKGFEWVADDDGTVYQSTSLSPEAVEVLQQQRERFVATFGREPGPDEPIFFDAPPVEQIEFQMVQAMTAAGIDPAIIYAYEKSGGL…
A0A1Q9V068 10-123 PTGRQYSWDAEPETGVQMADVLRRRRALFVETFGREPAPEDPLFFDADAREPRPLEELDFDWDMIFEAFDATGIDPAYAEAWRELGY…
A0A495P5K7 2-109 None
A0A7Z9WHQ3 19-142 None
A0A7K0IBL3 18-143 None
A0A6N6T438 9-113 None
Q029C8 3-101 None
A0A7W4J3J0 1-100 None
A0A7W1A0Q6 1-97 None
A0A6M8WSH0 30-146 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.