DPCstruct | MC12297

Metacluster Properties and Pfam Annotations

Number of structural domains363
Mean domain length (aa)148 ± 22 aa
Standard deviation of domain lengths21.56
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.50
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.47
Pfam Score99.75
Assigned Pfam label(s) PF18885- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S1SJA0 149-293 None
A0A0K0G3P9 34-203 None
A0A0N7JFR3 53-213 None
S8DV28 30-126 None
S8DUZ9 48-179 None
A0A2U1XRC4 7-153 None
A0A2R5GPH1 54-224 None
A0A522BCF0 306-450 None
A0A220S894 29-176 None
E3LM26 161-352 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.