DPCstruct | MC12297

Metacluster Properties and Pfam Annotations

Number of structural domains363
Mean domain length (aa)148 ± 22 aa
Standard deviation of domain lengths21.56
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.50
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.47
Pfam Score99.75
Assigned Pfam label(s) PF18885- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S8HW01 13-133 AAKALANHHPLYRSWNGSDHFYTSSKAEYDGLPNKYKREGIACYVATTKIPGHTELYRLYKGKIDDHFYTTSSSEKNKAVSSYGYKY…
A0A838UJL8 6-110 VRTEAYVLTEAGEGTLPLKLYWNEAVGDHATVATAEGERDALAGGYAFEGSQGFVYAEPRPGTVPLKQFWNAANRRSLLTATPKEEA…
A0A6N9RBR7 42-219 None
A0A1D7QL67 44-199 None
K9Z2U8 301-466 None
K9Z2R5 580-751 None
R2T0Z4 17-165 None
R9LPU2 342-478 None
R9LLN0 2-112 None
D8LKG0 297-454 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.