DPCstruct | MC12295

Metacluster Properties and Pfam Annotations

Number of structural domains662
Mean domain length (aa)116 ± 25 aa
Standard deviation of domain lengths24.93
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.57
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.10
Pfam Score90.36
Assigned Pfam label(s) CL0123- CL0291- CL0260- PF13427

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y5SJT3 6-113 None
A0A1F2S4H0 886-983 None
A0A7W5EUZ1 6-101 None
A0A1V4WGQ7 416-548 None
A0A2M7MV24 38-220 None
A0A0K1E547 117-232 None
A0A7Y8LNQ0 264-402 None
A0A7C5JKS4 123-236 None
A0A2W5YGX1 16-101 None
A0A239V9E2 11-122 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.