DPCstruct | MC12295

Metacluster Properties and Pfam Annotations

Number of structural domains662
Mean domain length (aa)116 ± 25 aa
Standard deviation of domain lengths24.93
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.57
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.10
Pfam Score90.36
Assigned Pfam label(s) CL0123- CL0291- CL0260- PF13427

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1M5FJV3 107-246 None
A0A2A5P0X2 7-121 None
A0A520W539 210-369 None
W6THH5 182-292 None
A0A3S4IYV0 134-334 None
A0A7W0S0U7 9-121 None
A0A139P599 3-142 None
A0A545VY54 16-129 None
A0A7K3J1E1 17-123 None
A0A0S8F9G6 2-118 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.