DPCstruct | MC12295

Metacluster Properties and Pfam Annotations

Number of structural domains662
Mean domain length (aa)116 ± 25 aa
Standard deviation of domain lengths24.93
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.57
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.10
Pfam Score90.36
Assigned Pfam label(s) CL0123- CL0291- CL0260- PF13427

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0N0I4S4 255-368 None
A0A651E0L8 19-188 None
L8GPN3 13-126 None
L8GVS4 22-139 None
L8GYG1 1-158 None
A0A1G3X878 192-292 None
A0A2D4VH63 181-283 None
A0A7C5KE56 35-134 None
A0A2H0Q3V7 1-90 None
A0A6L6PVC8 28-113 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.