DPCstruct | MC12295

Metacluster Properties and Pfam Annotations

Number of structural domains662
Mean domain length (aa)116 ± 25 aa
Standard deviation of domain lengths24.93
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.57
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.10
Pfam Score90.36
Assigned Pfam label(s) CL0123- CL0291- CL0260- PF13427

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1F6CZP8 6-112 EKTAREFAAEAVEALGEHIYSIVLYGSVVRGEASDESDIDVLVIGDGQSGAEDRVLDISYEIDLRNRTATSIFYSTPEDFERRLKLG…
A0A7H4NWG1 209-390 TWLAEAMIDAVVQQAWLQMVARYGQPTHLHERQGRGFAVVGYGKLGGWELGYSSDLDLVFLHDCPMEVMTDGEREIDGRQFYLRLAQ…
A0A357T657 14-121 None
A0A1G6JC53 1-114 None
A0A250KYF8 217-360 None
A0A1V4WNF8 152-269 None
A0A847PFE3 14-140 None
A0A2A7D1W8 5-85 None
M0D1F5 38-152 None
A0A7C7QTK8 2-111 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.