DPCstruct | MC12294

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)99 ± 14 aa
Standard deviation of domain lengths13.58
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score90.95
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)37.25
Pfam Score100.00
Assigned Pfam label(s) CL0125

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1F6CYU1 19-91 VCLVHDPRPTSPVGKTFTVEFLGNVIGGGIVQYLNVDIDLMKQIAMRKIVDGEPVWMGCDVGKMMQRKLGLWD
A0A4Z2H2V2 36-128 LTPRDFYQEHVKPLYNIHDKVCLVNDPRPQNPYAKLYSVEFLGNMVGGRPTQYNNQAIQLLKKAAADSIKDGEAVWFGCDVGKHFHG…
A0A5Q5FYY0 2-85 None
A9UPL3 236-343 None
A0A7R8CRY9 151-256 None
X6PD93 133-232 None
A0A0W4ZEP7 275-391 None
A0A6F9CGG2 195-301 None
A0A1J8QMG4 41-125 None
H3C8X2 5-93 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.