DPCstruct | MC12285

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)146 ± 18 aa
Standard deviation of domain lengths18.08
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score68.95
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)37.70
Pfam Score100.00
Assigned Pfam label(s) CL0271

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A835DNJ0 164-315 TVGDEKMKKRKGEEEKEIQEETGFLNFDEDLLFEVLKHVDARSLATAACVSKQWCRTVQDERLWEIICTRHWANIGCGDQRLRSVVL…
A0A2U1KA35 9-114 ENMTTLNTDLFYDILRRLDGATLASASCACAAFSSMSKEEKIWENICSSMWPSTKNDDVKTLISSIGGFKKFYADCFPLIVNKSVPD…
A0A2I0LG33 1-139 None
A0A151RPG5 1-147 None
A0A7C8Z7B9 74-219 None
A0A5A7PLQ1 3-126 None
A0A1D6Q3S6 79-219 None
A9LY11 1-153 None
A0A835IN13 9-159 None
A0A835RBP7 1-111 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.