DPCstruct | MC12284

Metacluster Properties and Pfam Annotations

Number of structural domains112
Mean domain length (aa)88 ± 14 aa
Standard deviation of domain lengths14.29
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score71.98
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)40.65
Pfam Score99.02
Assigned Pfam label(s) CL0123- CL0573

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A835DKX3 1-84 MGSWSAKQNKSFERALAIFDKDTPERWHNVASMVGGGKSTEEVKRHYDDLVEDLKCIESGQVPFPNYKPIAPSSKPKPPPPSHL
A0A2J6L5E5 4-88 VNWSWDENKIFENALTLYPEDAENRWELIAELLPGKTAQDVKAQYQKLIQDLEAIEAGLVPLPAYREFSEEEMAEARKKLAEEQE
K4AHE5 2-80 None
A0A6A6LJQ0 1-83 None
A0A166CBD6 114-203 None
A0A5N6Q932 524-625 None
A0A1U7Y6T4 1-93 None
A0A445J157 369-434 None
A0A834SIF0 2-95 None
A0A6P6GDD2 2-66 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.