DPCstruct | MC12280

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)224 ± 27 aa
Standard deviation of domain lengths26.91
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score82.46
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)61.51
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3XCZ6 3-185 DSIIKVYGALRVSVKMLLMLQSEIQVDGGGSTVVTTSVLEVRNLVVLKGKSVISSNANLALYGQGLLRLTGDGDAIIGQRLSLSLFY…
A0A835D457 15-278 LANLIWRYNSVYGAFRMAVKMLLMWNSEIQIDGGGNTIVTSSVLEVRNLVVLREKSVIGSNANLGVCGQGLLKLTGHGDAIKAQRLS…
A0A446IQS4 147-327 None
A0A453E6Z2 48-291 None
A0A453E6Z4 357-600 None
A0A438DSL8 1-245 None
A0A3L6PUQ6 3-170 None
A0A6P6SHP1 103-318 None
A0A2I0X436 377-624 None
A0A453A9X6 143-375 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.