DPCstruct | MC12278

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)173 ± 43 aa
Standard deviation of domain lengths42.87
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score81.73
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)21.28
Pfam Score100.00
Assigned Pfam label(s) PF19553

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X6VFT2 6-138 QYSCEYISEVCLVTILELQESHYIIKKCGNCGKYFIPYNRADTIYCDNISPQDDKRTCKEYGSQKLWYDKLKQDEAKKLYRNIYMAK…
A0A3D1RIN1 61-192 EIKELYEIKDMNDLIRFELLKFVSSDIEFKECENCHQYFIPVNRKDEIYCNRPIKGTEKTCKDVGAMNRHKEKAGDIPGEKEYWRVY…
A0A1G4WXE2 61-228 None
A0A412L754 18-181 None
A0A645C174 58-256 None
A0A1Y4IWY6 271-474 None
A0A1V5XA93 64-238 None
A0A1V5XGY5 84-305 None
A0A1Y4LI95 176-334 None
A0A1C0BHX4 9-116 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.