DPCstruct | MC12277

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)165 ± 17 aa
Standard deviation of domain lengths17.39
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score80.73
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)19.63
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C1IWJ7 22-186 DEQPSDRMLAILSMLYLLVMVGVFLWGMFDVWVGRYTVVRWLGYGSEVEMQRLEEPIFRLLAYAFLGGGVGGAVNGIRSLLTWHVEW…
A0A2W1AU92 110-277 DPDPWSAPILAMYLLAFGIAGLLAAVSQWSDVRALTDNDPETVAALRPNILLGLDWQVGGEELLLIFVASIGVFFGCLAGLRTAATY…
A0A3M2FNB7 103-259 None
A0A164AQH0 10-152 None
K9RWF3 69-236 None
A0A0M2USI0 24-201 None
A0A1I6L1V6 13-142 None
A0A524K0W1 55-217 None
A0A3C0MYZ3 2-157 None
A0A3C0BTN5 70-254 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.