DPCstruct | MC12274

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)178 ± 26 aa
Standard deviation of domain lengths26.36
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.36
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)17.16
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V4HWG4 5-186 ESVLQDCQMYIDFLQKCDRGYFLTRGVLDKNVEIVRKEYSVAQRKPKTIGQELHDSLNMHFNEIFGWPVRNGLFCYGIRIDLEKEIK…
A0A223PAQ1 7-156 HDDWKPLSGGMLLYRGFSQKAPEDTVLVRSPTDRKPAHMPLSVQHQMDDWFEKELGTRFRQRSLFTTGSLDVARRYAGDHGEVRVIQ…
A0A1G0EHV7 9-172 None
W7TTV6 131-310 None
A0A5J4Z442 75-265 None
A0A0G4HTI5 153-346 None
A0A4Q3P1X4 16-154 None
A0A6M3IRT7 22-183 None
A0A1Z5JZE2 78-227 None
A0A094KYD3 20-196 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.