DPCstruct | MC12272

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)129 ± 6 aa
Standard deviation of domain lengths5.97
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score89.81
Mean fraction of residues predicted as intrinsically disordered0.90
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)43.28
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T4S721 1-129 MDDIQKDNINTPEESADLAKEISLAEDKKAAAQTLVDALLSEHAKQTLQTELDELTPIGSPQVNDENHNGVPDKEDSLFDETTKAYE…
A0A380IYL8 270-399 AGKDKKAEVEADGVVNPDEKSAVDGLNDVTTEKKGTATPLVDSLPEGPVKEALKARLDQVTTSEVTVNDADSNGKPDSQDAAEAAAE…
A0A263HHL7 1-111 None
A0A376Y5J2 42-171 None
A0A376Y371 61-190 None
A0A376Y320 434-563 None
A0A376ZSY6 287-419 None
I2SNP8 116-251 None
A0A7U2VUR7 35-168 None
A0A240BSQ1 56-188 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.