DPCstruct | MC12253

Metacluster Properties and Pfam Annotations

Number of structural domains138
Mean domain length (aa)86 ± 14 aa
Standard deviation of domain lengths13.80
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.64
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)29.43
Pfam Score85.64
Assigned Pfam label(s) CL0023- CL0346- PF00238- CL0020- PF16205

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3P7IT23 10-124 None
A0A397FP55 82-156 None
F8PIF2 489-585 None
A0A5N6KVC2 17-121 None
A0A7V9KCM1 107-190 None
A0A842SYG4 3-102 None
I7M6C7 24-119 None
A0A4Y9YM73 386-469 None
A0A426YSE5 1-70 None
U4U2X7 100-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.