DPCstruct | MC12246

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)72 ± 6 aa
Standard deviation of domain lengths6.37
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score84.54
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)60.08
Pfam Score87.50
Assigned Pfam label(s) PF00521- PF16898

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9JH90 72-144 ELVLFSNMDNERSIPSAVDGLKPGQRKVMYTCLKRNDKREIKVAQLAGSVAEHSAYHHGEQSLMSTIINLAQN
A0A817KRL1 131-199 NKELVLFSKPSTERAIPSIMDVLKPDQRKIMFVCFTKSLICEIKVAQLAGKVAENSDYHHDEQSLTNTI
T1GDZ7 367-439 None
A0A817CBT0 375-438 None
A0A820W2Q7 73-155 None
A0A820PZH8 83-149 None
A0A1D6HGY6 414-482 None
A0A833ZS66 624-695 None
A0A2G9UGT2 60-144 None
A0A2P6SP06 227-301 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.