DPCstruct | MC12245

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)134 ± 12 aa
Standard deviation of domain lengths12.27
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score86.13
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)29.70
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S4HKV7 80-206 GGTIGSLFFLLPAFFFEFAAFRPERDAELILLLNDIGWLLLITPAPPFLLQALSLGAAILTDKNATPIFPRWAGYFTLWVAVLLIPA…
A0A2J5HTD2 23-159 LQSSCGTAAGMSLAVIAPCFGATVYRLERDPALTQLLNDLSWLVFTVVTSQFATQEFAISFGILSDTRAKPLVPHWVAWVNSLLTLT…
A0A0Q8VAH2 4-143 None
A0A2T5M6J8 102-254 None
A0A7I8A192 2-134 None
A0A1V3X6X8 3-108 None
A0A7I7UQR2 81-222 None
A0A7I7UFH6 183-327 None
A0A841P1Y7 85-214 None
A0A841NKM2 2-124 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.