DPCstruct | MC12242

Metacluster Properties and Pfam Annotations

Number of structural domains57
Mean domain length (aa)127 ± 29 aa
Standard deviation of domain lengths28.52
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score78.96
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)32.91
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C9SMS6 17-108 AAGNFGTCTDPSIKFAAGLDGRKESAFIPNNLKDFGHGSAQKVGIIAGFICQRLSDSCKAPAAIQGTCAQASAAAVAATQNQAAADA…
A0A2J5HEZ1 100-203 TETVTSCPTSPPRFDYGNCSDPSISYEYGLEGSTEWQFITNNQKDFEHHPTDSIDTLMSHVCNRLRSPCNAPQSTVARCEASSQQVN…
S3BUJ8 144-235 None
A0A3N4KQ25 275-353 None
A0A438NE58 19-125 None
S3CZE9 629-719 None
E5A4Q0 340-480 None
A0A0B1NVJ8 254-350 None
A0A0G2FM18 168-260 None
A0A319EGC1 119-259 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.