DPCstruct | MC12238

Metacluster Properties and Pfam Annotations

Number of structural domains198
Mean domain length (aa)196 ± 43 aa
Standard deviation of domain lengths42.86
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score83.75
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)34.21
Pfam Score87.22
Assigned Pfam label(s) CL0323- PF04560- PF04997- PF04998- CL0410

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R5VIF3 1-97 MHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWAIEAFGAAHVLQEILTIKSDDVVGRSKAYEAIVKGEPMPTPGIPESLNVLLHE…
M5VU06 196-404 SQLWPDIDMPFSEVTGMRPDLNINPHAFPSRMAIGMLLESIAAKVLYSGVYGTELTCEIFIGPVYYQRLQHMVSDKFKIFSVHSTGM…
A0A7S1UKE4 32-256 None
A0A7I4DFK5 130-304 None
A0A7S0MES3 531-747 None
A0A6J5VR40 1-177 None
A0A0G0D8M1 4-126 None
A0A0N5CT39 12-151 None
A0A421JS00 36-190 None
A0A438DLS7 331-628 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.