DPCstruct | MC12227

Metacluster Properties and Pfam Annotations

Number of structural domains84
Mean domain length (aa)174 ± 24 aa
Standard deviation of domain lengths23.66
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score87.09
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)14.11
Pfam Score75.24
Assigned Pfam label(s) PF10679- PF13785

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A800J848 6-163 GPDQPIRPGDEAVFEGENHLVMGWMRYEGWDDEDRWRWDEWQLVSDSGTPRYLSWSGDEGWTLQTPIRPTPKVTRTGIKLEKGRATI…
A0A3M1IHZ6 47-203 SGVVEDGSPIQLGTVGKWNNIPFEVIGRIQLHYALGFWNEWHLDLNGESAWLSESNGNYVISKKVEALVPKAEELKVYSYVDIAGKA…
A0A1Z2KZX9 19-192 None
A0A356KTF2 191-350 None
A0A066ZC93 2-154 None
A0A661P1Q4 29-179 None
A0A1I1VQD1 86-252 None
A0A6J4JCE6 245-393 None
A0A2V6PT38 11-171 None
A0A3M9MCK7 29-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.