DPCstruct | MC12226

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)120 ± 17 aa
Standard deviation of domain lengths16.90
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score72.66
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)21.06
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y7DD01 3-96 LDGDAVASAVLTLVREQGLWRGTASELITYLRMLYPALTESAEAFPRQAAGFGAELRRVTPLLRAHGVEVTHLRKGKERKRLVCIAK…
A0A2A5E237 1-103 MDNSPAALAIYELMQEYPVWEKTAQDLLRELDKHNIDAWPKTPESLTHLLRRMTPAFEEFGLQVEFLPRERNRRLIRITNTEYSEGN…
A0A5C5XEQ7 119-251 None
A0A2T5EXD5 133-272 None
A0A354GKN5 47-181 None
A0A7X7F7N1 78-194 None
A0A372V1L5 54-188 None
A0A062VDA3 190-301 None
A0A836BL93 461-579 None
A0A645HP36 1-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.